PEG 20000 was selected as cross-linking agent to prepare cross-linked sodium hyaluronate gel (CHA).Granulated CHA was obtained after a series of technologies:ethanol precipitation,drying,intermittent and instantaneous granulation,screening,redissolving and high-pressure steam sterilization.With the enzyme-resistant degradation rate of gel as index,effects of ethanol amount,drying temperature and drying time on preparation technology were investigated by orthogonal test.The optimum conditions of preparation technology were that the amount of 95% ethanol was 6.5 times of gel,drying the precipitation for 5.0h at 50.0℃。The enzyme-resistant degradation ratio of the granulated CHA was 80.53%,and the sodium hyaluronate(HA)hydrogel was 38.54%.
Reference from Journal of Henan University(Natural Science)
Writer:JIA Ke,ZHAO Yongliang,WANG Weiguo
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singclean | 2017-08-30
Warm Hearts, Caring Hands: Singclean’s Double Ninth CelebrationSingclean celebrates the Double Ninth Festival with the Blue Waterfront, Yisaka, Songdu Chenguang and other Communities, delivering "You & Me" care packages to honor the elderly and strengthen community bonds through cultural tradition. -
singclean | 2017-08-30
Singclean Medical to Showcase Innovative Biomaterial Solutions at MEDICA 2025, Düsseldorf, GermanyHangzhou, China – October 2025 — Singclean Medical, a leading developer and manufacturer of absorbable biomaterials, will participate in MEDICA 2025 from November 17th to 20th at the Messe Düsseldorf, Germany, located at Hall 16 / H67-3. -
singclean | 2017-08-30
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